Journal of atherosclerosis and thrombosis · 2003
Related factors of meeting National Cholesterol Education Program-recommended goals with atorvastatin.
Сравнительное исследованиеСтатьяНазвание и аннотация: Перевод пока не подготовлен
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Yoshitomi Yuji, Tsujibayashi Takashi, Ishii Toshikazu, Sakurai Shun-ichiro, Nagakura Chieko, Miyauchi Atsuyoshi, National Cholesterol Education Program
Аннотация
The aim of this study was to observe the efficacy of atorvastatin and the related factors of meeting the National Cholesterol Education Program (NCEP)-recommended low-density lipoprotein (LDL) cholesterol levels in patients with hypercholesterolemia. A total of 107 patients were treated with atorvastatin 10 mg/day for 12 weeks. Eighty % of the patients achieved the target goals. There was a significant difference in the initial body mass index (BMI) between patients achieving the target goals and those not achieving the target goals (p < 0.05). In multiple stepwise logistic regression analysis, initial BMI and complications correlated with reaching the NCEP-recommended target goals (p < 0.05). A great number of patients treated with atorvastatin, including those previously poorly controlled with other therapies, reached the target goals at the starting dose 10 mg/day. BMI may be a useful index of achieving the NCEP-recommended target goals with atorvastatin.