Clinical oral investigations · 2025
Six-year survival and clinical performance of glass hybrid restorations following selective caries removal in teeth with molar incisor hypomineralization: a prospective cohort study.
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Sezer Berkant, Şen Yavuz Betül, İşseven Ceyda İpek, Tuğcu Nihan, Çalışkan Cansu, Durmuş Başak, Kargül Betül
Аннотация
OBJECTIVES: This study aimed to evaluate the clinical success and long-term survival of glass hybrid restorations in permanent first molars affected by molar incisor hypomineralization (MIH) following selective caries removal (SCR) over a six-year follow-up period.
MATERIALS AND METHODS: This prospective cohort study included a total of 134 MIH-affected molars in 58 children (mean age 8.94 ± 1.41 years) restored with glass hybrid materials after SCR. Clinical outcomes were assessed at baseline and at 6, 12, 18, 24, and 72 months using modified USPHS criteria. Kaplan-Meier survival analysis and Cox proportional hazards regression with robust standard errors were conducted to evaluate restoration survival and identify potential predictors.
RESULTS: The overall estimated mean survival time of restorations was 59.82 ± 1.50 months. The survival probabilities for mild and severe lesions at six-year were 24.3% and 11.1%, respectively. Multivariate Cox proportional hazards regression with robust standard errors indicated that lesion severity, medium lesion extension, and large lesion extension had a statistically significant impact on restoration survival (p < 0.001 for all). While survival was satisfactory up to 2-3 years, a marked decline was observed over time, particularly in severely affected molars.
CONCLUSIONS: Glass hybrid restorations demonstrated acceptable clinical performance in MIH-affected molars in the short to medium term but showed significant limitations in long-term survival.
CLINICAL RELEVANCE: The need for advancements in restorative materials tailored to the structural challenges of MIH. Glass hybrid materials remain a viable option for managing MIH-affected molars, particularly in young patients where minimally invasive approaches are prioritized.
MATERIALS AND METHODS: This prospective cohort study included a total of 134 MIH-affected molars in 58 children (mean age 8.94 ± 1.41 years) restored with glass hybrid materials after SCR. Clinical outcomes were assessed at baseline and at 6, 12, 18, 24, and 72 months using modified USPHS criteria. Kaplan-Meier survival analysis and Cox proportional hazards regression with robust standard errors were conducted to evaluate restoration survival and identify potential predictors.
RESULTS: The overall estimated mean survival time of restorations was 59.82 ± 1.50 months. The survival probabilities for mild and severe lesions at six-year were 24.3% and 11.1%, respectively. Multivariate Cox proportional hazards regression with robust standard errors indicated that lesion severity, medium lesion extension, and large lesion extension had a statistically significant impact on restoration survival (p < 0.001 for all). While survival was satisfactory up to 2-3 years, a marked decline was observed over time, particularly in severely affected molars.
CONCLUSIONS: Glass hybrid restorations demonstrated acceptable clinical performance in MIH-affected molars in the short to medium term but showed significant limitations in long-term survival.
CLINICAL RELEVANCE: The need for advancements in restorative materials tailored to the structural challenges of MIH. Glass hybrid materials remain a viable option for managing MIH-affected molars, particularly in young patients where minimally invasive approaches are prioritized.