PLoS neglected tropical diseases · 2016
Molecular Epidemiology of Agents of Human Chromoblastomycosis in Brazil with the Description of Two Novel Species.
СтатьяПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод в очереди
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Gomes Renata R, Vicente Vania A, Azevedo Conceição M P S de, Salgado Claudio G, da Silva Moises B, Queiroz-Telles Flávio, Marques Sirlei G, Santos Daniel W C L, de Andrade Tania S, Takagi Elizabeth H, Cruz Katia S, Fornari Gheniffer, Hahn Rosane C, Scroferneker Maria L, Caligine Rachel B, Ramirez-Castrillon Mauricio, de Araújo Daniella P, Heidrich Daiane, Colombo Arnaldo L, de Hoog G S
Аннотация
The human mutilating disease chromoblastomycosis is caused by melanized members of the order Chaetothyriales. To assess population diversity among 123 clinical strains of agents of the disease in Brazil we applied sequencing of the rDNA internal transcribed spacer region, and partial cell division cycle and β-tubulin genes. Strains studied were limited to three clusters divided over the single family Herpotrichiellaceae known to comprise agents of the disease. A Fonsecaea cluster contained the most important agents, among which F. pedrosoi was prevalent with 80% of the total set of strains, followed by 13% for F. monophora, 3% for F. nubica, and a single isolate of F. pugnacius. Additional agents, among which two novel species, were located among members of the genus Rhinocladiella and Cyphellophora, with frequencies of 3% and 1%, respectively.