Ocular immunology and inflammation · 2025
Bilateral Secondary Glaucoma Associated with Congenital Herpes Simplex Virus Keratitis: A Case Report and Review of the Literature.
Клинический случайСтатьяОбзорНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
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Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Shah Rohan, Jang Kim Inae, Oh Lewis, Abbasian Javaneh, Farooq Asim V
Аннотация
PURPOSE: To highlight a relatively underappreciated yet significant complication of neonatal ocular herpes simplex virus (HSV) infection.
METHODS: Observational case report of a 4-week-old patient with congenital ocular HSV infection over the course of 6-year follow-up.
RESULTS: We describe a case of a neonate who developed bilateral HSV keratitis who subsequently developed bilateral glaucoma 9 months following primary infection. This patient ultimately required multiple goniotomies and glaucoma drainage device placement to achieve IOP control.
CONCLUSIONS: We hypothesize that the combination of initial HSV infection and associated inflammation damaged the trabecular meshwork and led to peripheral anterior synechiae, ultimately reducing outflow in this patient's developing eyes. This case is an example of a potentially underappreciated manifestation of congenital ocular HSV and its complications.
METHODS: Observational case report of a 4-week-old patient with congenital ocular HSV infection over the course of 6-year follow-up.
RESULTS: We describe a case of a neonate who developed bilateral HSV keratitis who subsequently developed bilateral glaucoma 9 months following primary infection. This patient ultimately required multiple goniotomies and glaucoma drainage device placement to achieve IOP control.
CONCLUSIONS: We hypothesize that the combination of initial HSV infection and associated inflammation damaged the trabecular meshwork and led to peripheral anterior synechiae, ultimately reducing outflow in this patient's developing eyes. This case is an example of a potentially underappreciated manifestation of congenital ocular HSV and its complications.