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Iranian journal of allergy, asthma, and immunology · 2014

Allergic and nonallergic asthma in children: are they distinct phenotypes?

Клиническое исследованиеСравнительное исследованиеСтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
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Mahdaviani Seyed Alireza, Mohajerani Seyed Amir, Fakhri Mohammad, Ebrahimi Mazaher, Bashardoost Bahram, Razavi Seyed Jafar, Toolabi Masoumeh, Tajik Ali, Khalilzadeh Soheila, Masjedi Mohamad Reza

Аннотация

The aim of current study is to describe clinical similarities and differences between atopic and non-atopic asthma in children. In a cross-sectional study, 95 asthmatic children (75 allergics and 20 nonallergics) were included in the study. Demographic, clinical, and familial history were compared between two groups. There was no significant differences between variables like sex, age of onset (p=0.75), severity (p=0.70), and family history among the two groups (p=0.42). Patients with allergic asthma were significantly older than those with non- allergic asthma (11.28 ± 3.19 and 9.75 ± 2.35 years, respectively, p=0.02). The controversy lingers over the presence of a completely distinct phenotype of non-atopic asthma in children. Our study suggested that phenotypes of allergic and non-allergic asthma in children were not entirely distinct.

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