Current pharmaceutical biotechnology · 2025
The Hepatoprotective Effects of Ginsenoside from Ginseng: A Review of Molecular Mechanisms and Therapeutic Potentials.
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Taha Seyed Reza, Fazlollahpour-Naghibi Andarz, Zadeh Mahdieh Shariat, Bagheri Kimia, Youshanlouei Hamed Rahmani, Mosaddeghi-Heris Reza, Hejazian Seyyed Sina, Khalaji Amirreza, Alavi Seyedeh Shaghayegh, Fattahi Payam, Mehrtabar Saba
Аннотация
Treatment of hepatic diseases presents a significant challenge due to their diverse nature. Ginsenosides, bioactive compounds derived from the root of Panax ginseng and widely used in traditional Chinese medicine, offer multifaceted protection to various organs in the body. Their versatile effects, including antioxidant, anti-inflammatory, anti-apoptotic and more, make them a promising approach for addressing hepatic disorders. This review explores the intricate molecular mechanisms and properties of ginsenosides in the prevention and treatment of liver diseases, from mild conditions to severe damage and liver fibrosis. Given the increasing prevalence of hepatic disorders, this article sheds light on the significant pharmaceutical potential of ginsenosides in the realm of hepatic disease management.