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Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi · 2010

[Safety and epidemiological effects of the first China-made mass A (H1N1) influenza vaccination].

Аннотация на английскомСтатьяНазвание и аннотация: Перевод пока не подготовлен
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Ji Wen-yan, Lu Li, Lü Min, Miao Liang, Gao Ting, Huang Ruo-gang, Suo Luo-dan, Liu Dong-lei, Ma Rui, Yu Rui, Zhangzhu Jia-zi, Liu Wei-xiang, Zeng Yang, Li Xiao-mei, Wu Jiang

Аннотация

OBJECTIVE: To evaluate the safety and epidemiological effects on the first mass vaccination program, using the China-made A (H1N1) influenza vaccine.

METHODS: Descriptive epidemiology and cohort study design were used to assess the influenza A H1N1 vaccine on its safety and epidemiological effects.

RESULTS: 95 244 subjects were immunized with A (H1N1) influenza vaccine. 193 adverse events were reported through AEFI Management System, with the Reported rates of AEFI as 2.03‰. Most of the adverse events (137/193, 71.0%) happened during the first 24 hours after immunization was carried out. Of 81 adverse reactions confirmed to be related to immunization, with 78 (96.3%) showed mild reactions. No Guillain-Barre Syndrome related to vaccination was reported through the AEFI Management System. The epidemiological protection rate of A (H1N1) vaccine could reach 80.9% when the coverage was not considered.

CONCLUSION: The A (H1N1) influenza vaccine showed a similar safety profile to seasonal flu vaccine. The vaccine demonstrated a good epidemiological effects against A (H1N1) influenza virus infection.

Предметные рубрики MeSH

ИП Урсолов Владлен Сергеевич

ИНН 500118482352 · ОГРНИП 314500117700049

Реквизиты и контакты