Repeat it without me: Crowdsourcing the T1 mapping common ground via the ISMRM reproducibility challenge.
Обработка статьи · этапы, ошибки и управление
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Boudreau Mathieu, Karakuzu Agah, Cohen-Adad Julien, Bozkurt Ecem, Carr Madeline, Castellaro Marco, Concha Luis, Doneva Mariya, Dual Seraina A, Ensworth Alex, Foias Alexandru, Fortier Véronique, Gabr Refaat E, Gilbert Guillaume, Glide-Hurst Carri K, Grech-Sollars Matthew, Hu Siyuan, Jalnefjord Oscar, Jovicich Jorge, Keskin Kübra, Koken Peter, Kolokotronis Anastasia, Kukran Simran, Lee Nam G, Levesque Ives R, Li Bochao, Ma Dan, Mädler Burkhard, Maforo Nyasha G, Near Jamie, Pasaye Erick, Ramirez-Manzanares Alonso, Statton Ben, Stehning Christian, Tambalo Stefano, Tian Ye, Wang Chenyang, Weiss Kilian, Zakariaei Niloufar, Zhang Shuo, Zhao Ziwei, Stikov Nikola, ISMRM Reproducible Research Study Group and the ISMRM Quantitative MR Study Group
Аннотация
METHODS: The challenge used the acquisition protocol from Barral et al. (2010). Researchers collected T1 mapping data on the ISMRM/NIST phantom and/or in human brains. Data submission, pipeline development, and analysis were conducted using open-source platforms. Intersubmission and intrasubmission comparisons were performed.
RESULTS: Eighteen submissions (39 phantom and 56 human datasets) on scanners by three MRI vendors were collected at 3 T (except one, at 0.35 T). The mean coefficient of variation was 6.1% for intersubmission phantom measurements, and 2.9% for intrasubmission measurements. For humans, the intersubmission/intrasubmission coefficient of variation was 5.9/3.2% in the genu and 16/6.9% in the cortex. An interactive dashboard for data visualization was also developed: https://rrsg2020.dashboards.neurolibre.org.
CONCLUSION: The T1 intersubmission variability was twice as high as the intrasubmission variability in both phantoms and human brains, indicating that the acquisition details in the original paper were insufficient to reproduce a quantitative MRI protocol. This study reports the inherent uncertainty in T1 measures across independent research groups, bringing us one step closer to a practical clinical baseline of T1 variations in vivo.