Медицинская библиотека · Head & neck · 2020

Parotid gland stem cells: Mini yet mighty.

Sari Sezin Yuce, Yilmaz Melek Tugce, Elmali Aysenur, Yedekci Fazli Yagiz, Yuce Deniz, Ozyigit Gokhan, Cengiz Mustafa, Yazici Gozde

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Аннотация

BACKGROUND

Our aim was to evaluate the correlation between the radiation doses to parotid gland (PG) stem cells and xerostomia.

METHODS

Patients diagnosed with head and neck cancer (HNC) were retrospectively evaluated, and xerostomia inventory (XI) was applied to these patients. PG stem cells were delineated on the treatment planning CT, and the mean doses to the PG stem cells calculated.

RESULTS

The total test score and mean doses to bilateral PGs were significantly correlated (r = .34, P = .001), and the mean doses to bilateral PG stem cell niches were significantly correlated with the total test score (r = .32, P = .002).

CONCLUSIONS

In this study, we found that the mean dose to PG stem cells can predict dry mouth as much as the mean dose to the PG.

Для цитирования: Sari Sezin Yuce, Yilmaz Melek Tugce, Elmali Aysenur, Yedekci Fazli Yagiz, Yuce Deniz, Ozyigit Gokhan, Cengiz Mustafa, Yazici Gozde. Parotid gland stem cells: Mini yet mighty.. Head & neck. 2020. DOI: 10.1002/hed.26556.

Предметные рубрики MeSH

Head and Neck Neoplasms Humans Parotid Gland Radiotherapy Dosage Radiotherapy, Intensity-Modulated Retrospective Studies Stem Cells Xerostomia

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