Phenotyping 1488 patients with painful temporomandibular disorders and its relevance to subjective sleep quality: A key step for stratified medicine.

Objective

To investigate biopsychosocial characteristics and sleep quality among three TMD phenotypes and to identify the influential factors on sleep quality among those patients.

Methods

Retrospective data from chart review and self-reported questionnaires included demographics, the Brief Pain Inventory, the Pain CatastropPain Prospective Evaluation and Risk Assessmenthizing Scale, the Symptom Check List-90 Revised, and the Pittsburgh Sleep Quality Index.

Results

A total of 1488 patients with painful TMD (female, 63.8%) were included and stratified into three groups: joint pain (n = 570), muscle pain (n = 542), and joint-muscle combined pain (n = 376). There were significant differences among demographic characteristics, pain experience, pain catastrophizing, and psychological distress of the three groups. Poor sleep quality presented in 78.4% of all patients. Sleep quality was significantly associated with TMD phenotypes, sex, and a helplessness component of pain catastrophizing.Discussion: This patient-centered and stratified approach will allow clinicians to come one step closer to personalized medicine.