BMC research notes · 2021
Variations in cervico-vaginal microbiota among HPV-positive and HPV-negative asymptomatic women in Peru.
СтатьяНазвание и аннотация: Перевод пока не подготовлен
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Carrillo-Ng Hugo, Becerra-Goicochea Lorena, Tarazona-Castro Yordi, Pinillos-Vilca Luis, Del Valle Luis J, Aguilar-Luis Miguel Angel, Tinco-Valdez Carmen, Silva-Caso Wilmer, Martins-Luna Johanna, Peña-Tuesta Isaac, Aquino-Ortega Ronald, Del Valle-Mendoza Juana
Аннотация
OBJECTIVE: To characterize the cervicovaginal microbiota of HPV-positive and HPV-negative asymptomatic Peruvian women, by identifying the presence of 13 representative bacteria genus.
RESULTS: A total of 100 HPV-positive and 100 HPV-negative women were matched by age for comparison of microbiota. The following bacteria were more frequently identified in HPV-positive patients compared to HPV-negative: Eubacterium (68 vs 32%), Actinobacteria (46 vs 33%), Fusobacterium (11 vs 6%) and Bacteroides (20 vs 13%). A comparison between high-risk and low-risk genotypes was performed and differences were found in the detection of Actinobacteria (50 vs 33.33%), Bifidobacterium (50 vs 20.83%) and Enterococcus (50 vs 29.17%).
RESULTS: A total of 100 HPV-positive and 100 HPV-negative women were matched by age for comparison of microbiota. The following bacteria were more frequently identified in HPV-positive patients compared to HPV-negative: Eubacterium (68 vs 32%), Actinobacteria (46 vs 33%), Fusobacterium (11 vs 6%) and Bacteroides (20 vs 13%). A comparison between high-risk and low-risk genotypes was performed and differences were found in the detection of Actinobacteria (50 vs 33.33%), Bifidobacterium (50 vs 20.83%) and Enterococcus (50 vs 29.17%).