Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica · 2005
[The effect of muscovite on the quality of gastric ulcer healing].
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Si Jian-Min, Qian Yun, Wu Jia-Guo
Аннотация
OBJECTIVE: To explore the effect of muscovite on the quality of gastric ulcer healing.
METHOD: Gastric ulcers were produced in male rats by serosal application of acetic acid. Rats were gavaged for 14 days with saline, omeprazole and muscovite starting 3 days after ulcer induction. Then the tissue and blood samples were obtained and measured.
RESULT: In the muscovite group, restored mucosa thickness increased, cystically dilated glands decreased, microvessels in connective tissue increased, the secretion of mucus, hexosamine, PGE2, EGF, bFGF were enhanced, and the express of EGFR was stronger.
CONCLUSION: Muscovite can promote the gastric ulcer healing and improve the quality of gastric ulcer healing.
METHOD: Gastric ulcers were produced in male rats by serosal application of acetic acid. Rats were gavaged for 14 days with saline, omeprazole and muscovite starting 3 days after ulcer induction. Then the tissue and blood samples were obtained and measured.
RESULT: In the muscovite group, restored mucosa thickness increased, cystically dilated glands decreased, microvessels in connective tissue increased, the secretion of mucus, hexosamine, PGE2, EGF, bFGF were enhanced, and the express of EGFR was stronger.
CONCLUSION: Muscovite can promote the gastric ulcer healing and improve the quality of gastric ulcer healing.