Contact lens & anterior eye : the journal of the British Contact Lens Association · 2026
Screening thresholds and the effects of age and sex on anterior chamber angle in a Chinese population: The examination of anterior chamber in Taiwan using swept-source OCT (EXACTS) study.
СтатьяНаблюдательное исследованиеНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Chen Kai-Yang, Chan Hoi-Chun, Chan Chi-Ming
Аннотация
INTRODUCTION: Primary angle-closure glaucoma (PACG) is a major cause of irreversible blindness and is expected to increase in aging Asian populations. This study established normative swept-source anterior segment optical coherence tomography (SS-ASOCT) measurements of anterior chamber angle (ACA) parameters in healthy Chinese individuals and derived percentile-based screening thresholds for referral, while evaluating the effects of age and sex on angle configuration.
METHODS: This observational cross-sectional study included 602 eyes from 301 healthy phakic Chinese participants without prior intraocular surgery, laser peripheral iridotomy, or corneal opacity. Participants were stratified by age (0-19, 20-39, 40-59, 60-79, and ≥ 80 years) and sex. Using SS-ASOCT (ANTERION®), ACA, scleral spur angle (SSA), angle opening distance (AOD), and trabecular-iris space area (TISA) were measured at 500 and 750 µm on the temporal and nasal sides. Values below the 20th percentile were considered provisional percentile-based screening thresholds for ophthalmologic or glaucoma specialist referral rather than diagnostic criteria for angle closure.
RESULTS: Mean age was 54.84 ± 19.22 years, 56.1% were female, and 45.0% were aged 60-79 years. Temporal parameters were consistently greater than nasal parameters at both 500 and 750 µm (all p < 0.001). For ACA500, the 10th percentile values were 20° temporally and 18° nasally, and the 20th percentile values were 27.2° and 25°, respectively; for SSA500, corresponding values were 20°/18° and 27°/24°. ACA showed strong positive correlations with SSA, AOD, and TISA (r = 0.800-0.950; all p < 0.001). All ACA-related parameters showed moderate negative correlations with age (r = -0.460 to -0.525; all p < 0.001), with marked narrowing from 40 years onward and generally lower values in older age groups. Males consistently demonstrated significantly wider angles than females across ACA, SSA, AOD, and TISA measurements at both distances.
CONCLUSION: ACA parameters vary significantly by age, sex, and meridian in phakic Chinese eyes. Values below the 20th percentile may serve as practical percentile-based screening thresholds for ophthalmologic or glaucoma specialist referral. Age-related narrowing is substantial from 40 years onward, while males exhibit wider angles than females.
METHODS: This observational cross-sectional study included 602 eyes from 301 healthy phakic Chinese participants without prior intraocular surgery, laser peripheral iridotomy, or corneal opacity. Participants were stratified by age (0-19, 20-39, 40-59, 60-79, and ≥ 80 years) and sex. Using SS-ASOCT (ANTERION®), ACA, scleral spur angle (SSA), angle opening distance (AOD), and trabecular-iris space area (TISA) were measured at 500 and 750 µm on the temporal and nasal sides. Values below the 20th percentile were considered provisional percentile-based screening thresholds for ophthalmologic or glaucoma specialist referral rather than diagnostic criteria for angle closure.
RESULTS: Mean age was 54.84 ± 19.22 years, 56.1% were female, and 45.0% were aged 60-79 years. Temporal parameters were consistently greater than nasal parameters at both 500 and 750 µm (all p < 0.001). For ACA500, the 10th percentile values were 20° temporally and 18° nasally, and the 20th percentile values were 27.2° and 25°, respectively; for SSA500, corresponding values were 20°/18° and 27°/24°. ACA showed strong positive correlations with SSA, AOD, and TISA (r = 0.800-0.950; all p < 0.001). All ACA-related parameters showed moderate negative correlations with age (r = -0.460 to -0.525; all p < 0.001), with marked narrowing from 40 years onward and generally lower values in older age groups. Males consistently demonstrated significantly wider angles than females across ACA, SSA, AOD, and TISA measurements at both distances.
CONCLUSION: ACA parameters vary significantly by age, sex, and meridian in phakic Chinese eyes. Values below the 20th percentile may serve as practical percentile-based screening thresholds for ophthalmologic or glaucoma specialist referral. Age-related narrowing is substantial from 40 years onward, while males exhibit wider angles than females.