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Anales de pediatria · 2020

[Characteristics of patients with invasive pneumococcal disease requiring admission to intensive care units].

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Díaz-Conradi Alvaro, García-García Juan José, González Peris Sebastià, Fernández de Sevilla Mariona, Moraga Llop Fernando, Ventura Paula Sol, Domínguez Angela, en representación del Grupo Barcino, Miembros del Grupo Barcino (Estudio de la Enfermedad Invasora Neumocócica en Cataluña), Domínguez Angela, Moraga Llop Fernando, de Sevilla Mariona Fernández, González Peris Sebastià, Ciruela Pilar, Campins Magda, Muñoz-Almagro Carmen, Esteva Cristina, Izquierdo Conchita, Uriona Sonia, Martínez Osorio Johanna, Solé Ribalta Anna, Codina Gemma, Soldevila Nuria, Salleras Sanmartí Lluís

Аннотация

INTRODUCTION: Patients with invasive pneumococcal disease (IPD) may require admission into paediatric intensive care units (PICU). The aim of this study is to analyse the epidemiological, clinical, and microbiological characteristics associated with IPD that may require admission to the PICU.

MATERIAL AND METHODS: A prospective study was conducted on cases of IPD diagnosed in three Paediatric Hospitals in Barcelona between January 2012 and June 2016. An analysis was made of the associations between the admission to PICU and the epidemiological, clinical, and microbiological variables.

RESULTS: A total of 263 cases with IPD were included, of which 19% (n = 50) required admission to PICU. Patients with septic shock (7; 100%), meningitis (16; 84.2%), and those with complicated pneumonia (23; 15.2%) were admitted to the PICU. The most frequent complications were pulmonary (35.2%) and neurological (39.5%). The ratio between admission and non-admission to PICU was 4.7 times higher in subjects with an underlying disease. The serotypes associated with PICU admission were 19A (23% of the total of this serotype), serotype 14 (20%), serotype 3 (17%), and serotype 1 (12.5%).

CONCLUSIONS: IPD required PICU admission in cases of septic shock and meningitis, and less so with complicated pneumonia. The percentage of admissions is greater in children with an underlying disease. Admission into the PICU involves a longer stay, complications during the acute phase, as well as sequelae, particularly neurological ones. The serotypes of the patients that were admitted to PICU were predominantly vaccine serotypes.

Предметные рубрики MeSH

ИП Урсолов Владлен Сергеевич

ИНН 500118482352 · ОГРНИП 314500117700049

Реквизиты и контакты