Terapevticheskii arkhiv · 2010
[Digestive system pathology in patients with chronic obstructive pulmonary disease concurrent with coronary heart disease].
Сравнительное исследованиеАннотация на английскомСтатьяНазвание и аннотация: Оригинал на русском
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Shoĭkhet Ia N, Klester E B
Аннотация
AIM: to study clinical and functional impairments in the digestive system in patients with chronic obstructive pulmonary disease (COPD), including that in the presence of coronary heart disease (CHD).
SUBJECTS AND METHODS: Clinical and functional impairments were analyzed in 1104 patients. Of them, 402 patients had COPD (Group 1); 459 had COPD concurrent with angina on exertion (Group 2); 243 had CHD (Group 3). All the patients suffered from cardiovascular diseases.
RESULTS: In patients with concomitant pathology, chronic gastritis is a most frequently detectable disease of the digestive system (62.3%), gastroenterological complaints being insignificant. The rate of Helicobacter pylori infection was 68.2% (in Group 2 patients) to 83.7% (in Group 1). A morphological study indicated that in concomitant pathology the number of patients with signs of atrophy increased; at the same time there were microcirculatory disorders in the gastric mucosa. Ulcerative disease was diagnosed in one third of the patients, a gastric ulcerative process being more commonly located in the stomach. Gastroesophageal reflux disease was detected in 206 (51.2%) patients in Group 1, in 267 (58.2%) in Group 2, and in 113 (46.5%) in Group 3.
CONCLUSION: By resulting in the mutual burden of the disease, the high rate of concomitant digestive pathology necessitates additional examination and mandatory medical correction in patients with
SUBJECTS AND METHODS: Clinical and functional impairments were analyzed in 1104 patients. Of them, 402 patients had COPD (Group 1); 459 had COPD concurrent with angina on exertion (Group 2); 243 had CHD (Group 3). All the patients suffered from cardiovascular diseases.
RESULTS: In patients with concomitant pathology, chronic gastritis is a most frequently detectable disease of the digestive system (62.3%), gastroenterological complaints being insignificant. The rate of Helicobacter pylori infection was 68.2% (in Group 2 patients) to 83.7% (in Group 1). A morphological study indicated that in concomitant pathology the number of patients with signs of atrophy increased; at the same time there were microcirculatory disorders in the gastric mucosa. Ulcerative disease was diagnosed in one third of the patients, a gastric ulcerative process being more commonly located in the stomach. Gastroesophageal reflux disease was detected in 206 (51.2%) patients in Group 1, in 267 (58.2%) in Group 2, and in 113 (46.5%) in Group 3.
CONCLUSION: By resulting in the mutual burden of the disease, the high rate of concomitant digestive pathology necessitates additional examination and mandatory medical correction in patients with