European journal of obstetrics, gynecology, and reproductive biology · 2025
Intracavitary-Electrohysterogram: Novel technique for assessing uterine peristalsis and electrophysiology in non-pregnant women.
СтатьяМногоцентровое исследованиеНазвание и аннотация: Перевод пока не подготовлен
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Alberola-Rubio Jose, Diaz-Martinez Alba, Mira-Tomas Juan Miguel, Faubel Pilar Alama, Sanz Sergio Caballero, Cortés Gemma Castillón, de Arriba-Garcia Maria, Aparicio Joaquín Llacer, Garcia-Casado Javier
Аннотация
BACKGROUND: Uterine peristalsis plays a crucial role in fertility and is affected by various disorders and pathologies. Its knowledge and assessment are very limited with current monitoring techniques.
OBJECTIVE: The aim is to objectively and quantitatively characterize menstrual uterine peristalsis using a new technique, intracavitary electrohysterogram (IC-EHG).
METHODS: This pilot multicenter study recorded IC-EHG by means of a multipolar catheter in a prospective cohort of 15 healthy women with proven fertility across three menstrual phases: mid-follicular (MF), early luteal (EL), and late luteal (LL). To describe and compare uterine peristaltic patterns, characteristics such as contraction frequency, duration, amplitude, and energy were calculated.
RESULTS: The IC-EHG recordings revealed statistically significant patterns throughout the menstrual phases. Uterine contractions were less frequent (3.2 CT/min), more intense and of longer duration during the MF phase. As the menstrual cycle progressed to the EL and LL phases, the frequency of contractions increased (3.7 and 3.5 CT/min, respectively) while both amplitude and duration declined.
CONCLUSIONS: The intracavitary electrohysterogram (IC-EHG) effectively quantifies menstrual cycle-dependent uterine peristalsis and electrophysiological patterns, providing initial reference values for uterine bioelectrical activity in fertile women. This novel technique represents a significant advance in assessing uterine physiology, with potential use as a diagnostic tool for real-time uterine health monitoring, supporting gynecological treatment and planning, and aiding in assisted reproductive technologies through objective metrics of uterine activity.
OBJECTIVE: The aim is to objectively and quantitatively characterize menstrual uterine peristalsis using a new technique, intracavitary electrohysterogram (IC-EHG).
METHODS: This pilot multicenter study recorded IC-EHG by means of a multipolar catheter in a prospective cohort of 15 healthy women with proven fertility across three menstrual phases: mid-follicular (MF), early luteal (EL), and late luteal (LL). To describe and compare uterine peristaltic patterns, characteristics such as contraction frequency, duration, amplitude, and energy were calculated.
RESULTS: The IC-EHG recordings revealed statistically significant patterns throughout the menstrual phases. Uterine contractions were less frequent (3.2 CT/min), more intense and of longer duration during the MF phase. As the menstrual cycle progressed to the EL and LL phases, the frequency of contractions increased (3.7 and 3.5 CT/min, respectively) while both amplitude and duration declined.
CONCLUSIONS: The intracavitary electrohysterogram (IC-EHG) effectively quantifies menstrual cycle-dependent uterine peristalsis and electrophysiological patterns, providing initial reference values for uterine bioelectrical activity in fertile women. This novel technique represents a significant advance in assessing uterine physiology, with potential use as a diagnostic tool for real-time uterine health monitoring, supporting gynecological treatment and planning, and aiding in assisted reproductive technologies through objective metrics of uterine activity.