[Chronic persistent hepatitis with an atypical clinical course].

Chronic persistent hepatitis is a form of chronic hepatitis with mild clinical course that does not require specific therapy. Diagnosis is established by liver biopsy. A 65 years old female patient, was admitted to the Clinic of gastroenterology with clinical and laboratory picture of obstructive jaundice with progressive deterioration. Obstruction was not found through performed examinations (US, CT, gastroduodenoscopy, ERCP). Viral liver infections as well as primary biliary cirrhosis were also excluded. Ultrasonically guided liver biopsy verified chronic persistent hepatitis. Specificity of this case was in atypical clinical course and treatment: obstructive jaundice clinical feature, rapid deterioration and corticosteroid treatment that led to the complete clinical and biochemical recovery.