Retina (Philadelphia, Pa.) · 2026
PREVALENCE, RISK FACTORS, AND OUTCOMES OF RHEGMATOGENOUS RETINAL DETACHMENTS REPAIR IN MARFAN SYNDROME.
СтатьяНазвание и аннотация: Перевод в очереди
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Nagshbandi Ahmed A, Magliyah Moustafa S, Algwaiz Abdulrahman F, Alhaidari Abdulmajeed I, Sallam Ahmed B, Badawi Abdulrahman H
Аннотация
PURPOSE: To report the prevalence, risk factors, and surgical management outcomes of rhegmatogenous retinal detachment (RRD) in Marfan syndrome.
METHODS: Retrospective chart review of 82 patients with Marfan syndrome who have developed RRD. The collected data included lens status, previous surgeries, details of intraoperative retinal findings, and follow-up outcomes.
RESULTS: The study included 163 eyes of 82 patients. Forty-three patients (52.4%) were males. The mean duration of follow-ups was 15.3 ± 13.4 years. RRD occurred in 54 eyes (33.1%). The mean age at the time of RRD was 25.2 ±12.5 years. Risk of RRD was significantly higher among patients who had previous trauma ( P = 0.014), previous ocular surgery ( P = 0.001), lensectomy without implantation of an intraocular lens ( P = 0.002), aphakia ( P < 0.001), lens subluxation ( P = 0.002), and higher axial length ( P < 0.001). Successful primary reattachment was achieved in 36 eyes (69.2%), whereas 16 eyes (30.8%) required secondary repairs to achieve reattachments.
CONCLUSION: Eyes with Marfan syndrome have a 33.1% risk of developing RRD upon long-term follow-ups. Previous trauma, intraocular surgeries, aphakic status, and high axial length are associated with higher risk. High reattachments rates could be achieved after surgical repairs.
METHODS: Retrospective chart review of 82 patients with Marfan syndrome who have developed RRD. The collected data included lens status, previous surgeries, details of intraoperative retinal findings, and follow-up outcomes.
RESULTS: The study included 163 eyes of 82 patients. Forty-three patients (52.4%) were males. The mean duration of follow-ups was 15.3 ± 13.4 years. RRD occurred in 54 eyes (33.1%). The mean age at the time of RRD was 25.2 ±12.5 years. Risk of RRD was significantly higher among patients who had previous trauma ( P = 0.014), previous ocular surgery ( P = 0.001), lensectomy without implantation of an intraocular lens ( P = 0.002), aphakia ( P < 0.001), lens subluxation ( P = 0.002), and higher axial length ( P < 0.001). Successful primary reattachment was achieved in 36 eyes (69.2%), whereas 16 eyes (30.8%) required secondary repairs to achieve reattachments.
CONCLUSION: Eyes with Marfan syndrome have a 33.1% risk of developing RRD upon long-term follow-ups. Previous trauma, intraocular surgeries, aphakic status, and high axial length are associated with higher risk. High reattachments rates could be achieved after surgical repairs.