PREVALENCE, RISK FACTORS, AND OUTCOMES OF RHEGMATOGENOUS RETINAL DETACHMENTS REPAIR IN MARFAN SYNDROME.

PURPOSE: To report the prevalence, risk factors, and surgical management outcomes of rhegmatogenous retinal detachment (RRD) in Marfan syndrome.

METHODS

Retrospective chart review of 82 patients with Marfan syndrome who have developed RRD. The collected data included lens status, previous surgeries, details of intraoperative retinal findings, and follow-up outcomes.

RESULTS

The study included 163 eyes of 82 patients. Forty-three patients (52.4%) were males. The mean duration of follow-ups was 15.3 ± 13.4 years. RRD occurred in 54 eyes (33.1%). The mean age at the time of RRD was 25.2 ±12.5 years. Risk of RRD was significantly higher among patients who had previous trauma ( P = 0.014), previous ocular surgery ( P = 0.001), lensectomy without implantation of an intraocular lens ( P = 0.002), aphakia ( P < 0.001), lens subluxation ( P = 0.002), and higher axial length ( P < 0.001). Successful primary reattachment was achieved in 36 eyes (69.2%), whereas 16 eyes (30.8%) required secondary repairs to achieve reattachments.

CONCLUSION

Eyes with Marfan syndrome have a 33.1% risk of developing RRD upon long-term follow-ups. Previous trauma, intraocular surgeries, aphakic status, and high axial length are associated with higher risk. High reattachments rates could be achieved after surgical repairs.