[Neuroleptics and nicotine].

Excessive smoking is a well know phenomenon in psychiatry. Nicotine, the most important content of cigarette tobacco, interacts with several receptors of neurotransmitters in the CNS: especially the dopaminergic system appears to be relevant in this respect. Nicotine is a potent substance to counteract neuroleptic-induced parkinsonism. On the other hand nicotine is possibly a risk-factor for tardive dyskinesia. Nicotine has enormous therapeutical implications.