[Central nervous disease and manic state].

We often observe several psychotic symptoms in physical illness-delusions, hallucinations, manic-depressive state and nervous state, for example. The purpose of this chapter is to account for the relationship between manic-depressive state and central nervous disease. Secondary mania is considered to occur in association with physical illness. The criteria for a diagnosis of it is a duration of at least one week, elated or irritable mood, and at least two of the following: hyperactivity, "push of speech", flight of ideas, gradiosity, decreased sleep, distractibility, and lack of judgement. Depressive state is often observed in infarction, infection, neoplasm, head injury and degenerative disease. The differential diagnosis of pseudodementia and pseudodepression are receiving increased attention, we showed the table of clinical characteristics for distinguishing pseudo-depression from pseudodementia.