[Change in lipid peroxidation processes and level of individual gangliosides and phospholipids in the liver of rats with toxic experimental hepatitis].

Content of individual phospholipids, gangliosides and lipid peroxidation were studied in liver tissue homogenates of rats with hepatitis caused by CCl4 or heliotrine. In all the cases studied the rate of lipid peroxidation was distinctly increased, while content of sphingomyelin was decreased and that of phosphatic acid--increased; concentration of some gangliosides was altered. Activation of lipid peroxidation appears to induce the enzymatic systems involved in degradation of phospholipids and gangliosides in liver tissue of rats with toxic hepatitis.