Impact of asthma severity on surgical outcomes in patients with chronic rhinosinusitis comorbid with asthma.

BACKGROUND

Patients with chronic rhinosinusitis with nasal polyps comorbid with asthma often experience poor outcomes after endoscopic sinus surgery.

OBJECTIVE

To evaluate the impact of asthma severity on the long-term outcomes after surgery in these patients.

METHODS

A total of 83 patients with chronic rhinosinusitis with nasal polyps comorbid with asthma who underwent endoscopic sinus surgery were prospectively enrolled in this study. Patients were classified into mild, moderate, and severe asthma groups based on their preoperative asthma severity. Clinical symptom scores, nasal endoscopy scores, and asthma control test results were recorded preoperatively and at 1 year and 12 years postoperatively.

RESULTS

A total of 71 patients completed the 12-year follow-up. All patients had significant improvement in nasal symptom scores and nasal endoscopy scores. However, 48 of 71 patients (67.6%) experienced nasal polyp recurrence, and 22 of them (31.0%) underwent revision surgery. Patients in the severe asthma group had the highest rate of nasal polyp recurrence (P = .02) and revision surgery (P = .01) and the least improvement in smell disturbance (P = .04) and general symptom (P = .02) compared with the other asthma groups.

CONCLUSION

Preoperative asthma severity significantly influenced the outcome of endoscopic sinus surgery in patients with chronic rhinosinusitis with nasal polyps comorbid with asthma, in whom endoscopic sinus surgery had a long-term beneficial effect.

TRIAL REGISTRATION: https://www.chictr.org.cn/: ChiCTR2100050583.