Scanning electron microscopy of jejunal biopsies in patients with untreated and treated coeliac disease.

Biopsy specimens of jejunal mucosa from children with coeliac disease (CD) were examined by scanning electron microscopy (SEM) and light microscopy (LM) before and after gluten-free diet. The results demonstrate that SEM is more sensitive than LM in documenting early morphological restoration of jejunal mucosa in patients treated with gluten-free diet.