Journal of the Indian Society of Pedodontics and Preventive Dentistry · 2025
Comparative evaluation of antimicrobial effectiveness of 2% chlorhexidine, 25% aqueous extract of propolis, and 2.4% curcuma longa as intracanal irrigants: An ex vivo study.
СтатьяСравнительное исследованиеНазвание и аннотация: Перевод пока не подготовлен
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Sengupta Upasana, Sogi H P Suma, Shah Syed Gulbar, Bala Rosy, Saini Reena, Garg Nancy, Jain Mansi
Аннотация
CONTEXT: The primary teeth's unique histological properties and interactions with the oral cavity pose a challenge in treatment, unlike the permanent teeth. A repaired natural tooth maintains space better than an artificial one. These factors lead to a greater emphasis on saving the tooth by pulpectomy involving effective chemical cleaning and disinfection of canals than on meticulous mechanical canal shaping. As chemically available irrigants show cytotoxic effects, hence herbal-based irrigants are being considered viable options.
AIM: The present study was undertaken to compare and assess the antimicrobial effect of 2.4% Curcuma longa extract, 25% aqueous propolis, and 2% chlorhexidine in deciduous teeth.
MATERIALS AND METHODS: Forty eight subjects in age range of 4-7 years were allocated equally into four groups - Group I: saline (Negative control), Group II: 2% chlorhexidine (Positive control), Group III: 2.4% Curcuma longa, and Group IV: 25% aqueous propolis based on inclusion and exclusion criteria. Isolation was achieved using a rubber dam. Pre and postirrigation samples were collected using sterile absorbent paper points and transferred to a test tube containing brain heart infusion. The pre and postirrigation samples were sent for microbial assay. Streptococcus mutans and Enterococcus faecalis were isolated using standard microbiological methods, and serial dilution method was done to determine the pre and post irrigation colony counts. The plates were duplicated and incubated at 37°C for 24 h. The preirrigation and post irrigation colony count samples with different irrigants were counted and compared.
STATISTICAL ANALYSIS: For the saline paired t-test was used to compare the pre- and postirrigation values, and for 2% chlorhexidine, 2.4% curcuma longa, and 25% aqueous extract of propolis groups. The Wilcoxon matched signed rank test was used to compare pre- and post-irrigation bacterial counts. To compare the mean change in bacterial colony counts ANOVA test was done.
RESULTS: S. mutans and E. faecalis were the most commonly isolated microorganisms. There was no statistical significant difference between saline, 2% chlorhexidine, 2.4% curcuma longa, and 25% aqueous extract of propolis.
CONCLUSION: The micro-organisms prevalent in primary teeth with necrosis included S. mutans and E. faecalis. Antimicrobial sensitivity testing done with the serial dilution method showed that herbal irrigants such as 2.4% Curcuma longa extract and propolis were equally effective as 2% chlorhexidine.
AIM: The present study was undertaken to compare and assess the antimicrobial effect of 2.4% Curcuma longa extract, 25% aqueous propolis, and 2% chlorhexidine in deciduous teeth.
MATERIALS AND METHODS: Forty eight subjects in age range of 4-7 years were allocated equally into four groups - Group I: saline (Negative control), Group II: 2% chlorhexidine (Positive control), Group III: 2.4% Curcuma longa, and Group IV: 25% aqueous propolis based on inclusion and exclusion criteria. Isolation was achieved using a rubber dam. Pre and postirrigation samples were collected using sterile absorbent paper points and transferred to a test tube containing brain heart infusion. The pre and postirrigation samples were sent for microbial assay. Streptococcus mutans and Enterococcus faecalis were isolated using standard microbiological methods, and serial dilution method was done to determine the pre and post irrigation colony counts. The plates were duplicated and incubated at 37°C for 24 h. The preirrigation and post irrigation colony count samples with different irrigants were counted and compared.
STATISTICAL ANALYSIS: For the saline paired t-test was used to compare the pre- and postirrigation values, and for 2% chlorhexidine, 2.4% curcuma longa, and 25% aqueous extract of propolis groups. The Wilcoxon matched signed rank test was used to compare pre- and post-irrigation bacterial counts. To compare the mean change in bacterial colony counts ANOVA test was done.
RESULTS: S. mutans and E. faecalis were the most commonly isolated microorganisms. There was no statistical significant difference between saline, 2% chlorhexidine, 2.4% curcuma longa, and 25% aqueous extract of propolis.
CONCLUSION: The micro-organisms prevalent in primary teeth with necrosis included S. mutans and E. faecalis. Antimicrobial sensitivity testing done with the serial dilution method showed that herbal irrigants such as 2.4% Curcuma longa extract and propolis were equally effective as 2% chlorhexidine.