Oral surgery, oral medicine, oral pathology and oral radiology · 2014
Benefits of an intraoral stent in decreasing the irradiation dose to oral healthy tissue: dosimetric and clinical features.
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Verrone Juliana Rocha, Alves Fabio Abreu, Prado José Divaldo, Marcicano Alessandra das Dores, de Assis Pellizzon Antonio Cassio, Damascena Aline Santos, Jaguar Graziella Chagas
Аннотация
OBJECTIVE: To determine whether an intraoral stent may decrease radiation dose to health tissues during intensity-modulated radiotherapy (IMRT) and to evaluate the effect on mucositis.
STUDY DESIGN: A total of 33 patients with tongue or floor of the mouth cancer were retrospectively evaluated and divided into 2 groups: group 1 (with stent, n = 19) and group 2 (without stent, n = 14). Data were collected on dosimetric and mucositis outcomes.
RESULTS: The mean dose to the maxilla was significantly lower in group 1 (20.9 Gy) than in group 2 (35.8 Gy) (P = .05). The mean dose to the ipsilateral parotid was 35.0 Gy in group 1 vs 41.8 Gy in group 2 (P = .05). No difference was seen in the severity of mucositis between groups (P = .82). However, grade III mucositis was present in group 1 at 4 weeks after IMRT, 1 week after its occurrence in group 2.
CONCLUSIONS: A stent was effective in decreasing doses to healthy structures and delaying the emergence of mucositis.
STUDY DESIGN: A total of 33 patients with tongue or floor of the mouth cancer were retrospectively evaluated and divided into 2 groups: group 1 (with stent, n = 19) and group 2 (without stent, n = 14). Data were collected on dosimetric and mucositis outcomes.
RESULTS: The mean dose to the maxilla was significantly lower in group 1 (20.9 Gy) than in group 2 (35.8 Gy) (P = .05). The mean dose to the ipsilateral parotid was 35.0 Gy in group 1 vs 41.8 Gy in group 2 (P = .05). No difference was seen in the severity of mucositis between groups (P = .82). However, grade III mucositis was present in group 1 at 4 weeks after IMRT, 1 week after its occurrence in group 2.
CONCLUSIONS: A stent was effective in decreasing doses to healthy structures and delaying the emergence of mucositis.
Предметные рубрики MeSH
AdultAgedAged, 80 and overDose-Response Relationship, RadiationFemaleHumansMaleMaxillaMiddle AgedMouth NeoplasmsMucositisNeoplasm StagingParotid GlandRadiation DosageRadiation InjuriesRadiation ProtectionRadiometryRadiotherapy, Intensity-ModulatedRetrospective StudiesSeverity of Illness IndexStentsTongue Neoplasms