Медицинская библиотека · Climacteric : the journal of the International Menopause Society · 2022

First live birth in China after cryopreserved ovarian tissue transplantation to prevent premature ovarian insufficiency.

Ruan X, Du J, Lu D, Duan W, Jin F, Kong W, Wu Y, Dai Y, Yan S, Yin C, Li Y, Cheng J, Jia C, Liu X, Wu Q, Gu M, Ju R, Xu X, Yang Y, Jin J, Korell M, Montag M, Liebenthron J, Mueck A O

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Аннотация

OBJECTIVE

This article reports the first live birth after cryopreserved ovarian tissue transplantation to prevent premature ovarian insufficiency in China.

METHODS

A patient with myelodysplastic syndrome received ovarian tissue cryopreservation before hematopoietic stem cell transplantation, and six ovarian cortex strips were thawed and transplanted into her peritoneal pocket 2 years later.

RESULTS

Pregnancy occurred spontaneously 27 months after grafting, and a healthy girl was born at 38 weeks gestation. Until now, the child has developed normally without any major diseases.

CONCLUSIONS

We report the first live birth resulting from ovarian tissue cryopreservation and transplantation in China.

Для цитирования: Ruan X, Du J, Lu D, Duan W, Jin F, Kong W, Wu Y, Dai Y, Yan S, Yin C, Li Y, Cheng J, Jia C, Liu X, Wu Q, Gu M, Ju R, Xu X, Yang Y, Jin J, Korell M, Montag M, Liebenthron J, Mueck A O. First live birth in China after cryopreserved ovarian tissue transplantation to prevent premature ovarian insufficiency.. Climacteric : the journal of the International Menopause Society. 2022. DOI: 10.1080/13697137.2022.2064215.

Предметные рубрики MeSH

Child Cryopreservation Female Fertility Preservation Humans Live Birth Menopause, Premature Pregnancy Primary Ovarian Insufficiency

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