Radiology · 1995
Characterization of adrenal masses with chemical shift and gadolinium-enhanced MR imaging.
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Korobkin M, Lombardi T J, Aisen A M, Francis I R, Quint L E, Dunnick N R, Londy F, Shapiro B, Gross M D, Thompson N W
Аннотация
PURPOSE: To assess the potential role of chemical shift and dynamic gadolinium-enhanced magnetic resonance (MR) imaging in the characterization of adrenal masses.
MATERIALS AND METHODS: Fifty-one adrenal masses (35 adenomas and 16 nonadenomas) in 43 patients were evaluated with chemical shift MR imaging, dynamic gadolinium-enhanced MR imaging, or both. The relative change in the signal intensity (SI) ratio of the adrenal mass to liver and paraspinal muscles was quantitatively and qualitatively assessed. Opposed-phase gradient-echo (GRE) images were compared with in-phase images.
RESULTS: With qualitative visual inspection, only adenomas showed a decrease in relative SI ratio on opposed-phase chemical shift images (specificity, 100%; sensitivity, 81%). Quantitative ratios corresponding to 100% specificity were also observed, with similar sensitivities. Adenomas could not be differentiated from nonadenomas with visual assessment of maximum SI after contrast material administration or washout.
CONCLUSION: Characterization of an adrenal mass as an adenoma can be made with high specificity and acceptable sensitivity by visually comparing opposed-phase with in-phase GRE images.
MATERIALS AND METHODS: Fifty-one adrenal masses (35 adenomas and 16 nonadenomas) in 43 patients were evaluated with chemical shift MR imaging, dynamic gadolinium-enhanced MR imaging, or both. The relative change in the signal intensity (SI) ratio of the adrenal mass to liver and paraspinal muscles was quantitatively and qualitatively assessed. Opposed-phase gradient-echo (GRE) images were compared with in-phase images.
RESULTS: With qualitative visual inspection, only adenomas showed a decrease in relative SI ratio on opposed-phase chemical shift images (specificity, 100%; sensitivity, 81%). Quantitative ratios corresponding to 100% specificity were also observed, with similar sensitivities. Adenomas could not be differentiated from nonadenomas with visual assessment of maximum SI after contrast material administration or washout.
CONCLUSION: Characterization of an adrenal mass as an adenoma can be made with high specificity and acceptable sensitivity by visually comparing opposed-phase with in-phase GRE images.
Предметные рубрики MeSH
AdenomaAdipose TissueAdrenal Gland NeoplasmsAdultAgedCarcinomaContrast MediaDrug CombinationsFemaleGadoliniumGadolinium DTPAHumansImage EnhancementLipidsLiverMagnetic Resonance ImagingMaleMeglumineMiddle AgedMuscle, SkeletalOrganometallic CompoundsPentetic AcidPheochromocytomaProspective StudiesSensitivity and SpecificitySignal Processing, Computer-Assisted