[Effect of anesthetized antral mucosa on anti-peristaltic discharge].

The origin of anti-peristaltic discharge occurred in the distal stomach of canine after transection followed by end-to-end anastomosis is uncertain. The purpose of this paper is to investigate electromyographically whether the mucosa of the distal stomach effects on the occurrence of anti-peristaltic discharge. By applying lidocaine to the lumen of the distal stomach after transection followed by end-to-end anastomosis, the retardation of propagation velocity of normo-peristaltic discharge and the decrease of frequency of anti-peristaltic discharge were noted on the antrum. On respect of frequency of anti-peristaltic discharge, the findings above were remarkable in the high appearant group (5 dogs; greater than or equal to 80%) compared with low appearant group (2 dogs; less than or equal to 60%). Conclusively, it was suggested that the occurrence of anti-peristaltic discharge was related to the enteric nervous system in the mucosa and/or submucosa.