Navigation-guided resection for a tenosynovial giant cell tumor involving the temporomandibular joint and skull base.

Tenosynovial giant cell tumor is a very rare, benign lesion from the synovium. It seldom happens in the temporomandibular joint area and skull base that is difficult to resect and reconstruct. We present a case treated with computer-assisted navigation to help mark the tumor boundaries, protect vital structures, and facilitate the reconstruction process. Follow-up at 6 months after surgery showed no tumor recurrent and good temporomandibular joint function.