Parasitic infections of the gut in children.

Parasitic infections of the gut have major implications for child health, but many questions remain unanswered. Protozoal parasites, especially cryptosporidiosis and giardiasis, cause diarrhoea and contribute to impaired growth, neurocognitive development and mortality. Entamoeba histolytica causes dysentery and may have more subtle effects on child growth. Helminth infections are mostly asymptomatic, and untargeted mass deworming has not been shown to be beneficial. However, children with heavy infections certainly benefit from antihelminthic treatment. Hepatosplenic schistosomiasis is a neglected problem on a massive scale, which causes portal hypertension and lifelong morbidity in individuals who get infected in childhood. Neurocysticercosis causes epilepsy and is a significant consequence of taeniasis solium, another neglected disease which is entirely preventable. Parasitic infections of the gut contribute to child health problems on a large scale. Fresh approaches are needed to prevention and treatment.