Microplastics and the Placenta: A Call to Action for Perinatal Research.

Microplastics have been detected in human placental and neural tissues, raising urgent concerns about their potential effects on maternal and fetal health. Emerging evidence links microplastics to systemic inflammation, neurotoxicity, and endocrine disruption, yet their impact on pregnancy outcomes and fetal development remains poorly understood. Given the placenta's central role in early-life health, perinatal researchers are uniquely positioned to lead investigations into this environmental threat. We call for collaborative, multidisciplinary research to better understand and mitigate the effects of microplastic exposure during pregnancy. · Microplastics can cross the placenta and blood-brain barrier, reaching fetal tissues.. · Microplastics trigger inflammation, oxidative stress, and endocrine disruption in human cells.. · Perinatal research should explore links between microplastics and fetal development risks..