The effect of short-term microgravity and hypergravity on eyelid and brow position.

PURPOSE: Spaceflights induce periocular facial changes which could contribute to ocular conditions which affect astronauts. This study is to validate parabolic flight as a suitable model for studying gravitational facial changes.

METHODS

Healthy participants (n = 13; 37 ± 10 years) underwent short-term exposure to microgravity and hypergravity during parabolic flight. Facial images were captured and differences in measurements from pupil center to upper and lower eyelid margins (MRD1 and MRD2), and to the inferior and superior eyebrow margin (PTBi and PTBs) under normogravity, microgravity, and hypergravity were compared. A repeated measures ANOVA with Bonferroni-Holm corrected post-hoc paired t-test was used for statistical analysis.

RESULTS

One hundred and twenty-seven images (44 normal gravity, 43 microgravity, 40 hypergravity) revealed that short-term microgravity induced a mean PTBi increase of 2.3 mm (p < 0.001) and mean PTBs increase of 2.4 mm (p < 0.001) while decreasing mean MRD2 by 0.9 mm (p < 0.001) but without change in MRD1 (p = 0.41). Short-term hypergravity did not change PTBs, PTBi or MRD2 but reduced mean MRD1 by 0.7 mm (p < 0.01).

CONCLUSIONS

Short-term microgravity, similar to spaceflight, significantly elevates PTB but not MRD1. It was also shown that MRD2 was reduced. Short-term hypergravity induces significant reductions only in MRD1. Phenomena are likely explicable by co-activation of the muscles raising the eyelid and eyebrow. Comparison to space data suggests that parabolic flight offers a valid model to study periocular facial changes in microgravity.