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DOI 10.1007/s00431-017-2924-x

Медицинская библиотека · European journal of pediatrics · 2017

Long-term outcomes of Heller's myotomy and balloon dilatation in childhood achalasia.

Saliakellis Efstratios, Thapar Nikhil, Roebuck Derek, Cristofori Fernanda, Cross Kate, Kiely Edward, Curry Joseph, Lindley Keith, Borrelli Osvaldo

Сравнительное исследованиеСтатьяПеревод пока не подготовлен

Аннотация

UNLABELLED: Achalasia is a rare esophageal motility disorder: its optimal treatment in children is still a matter of debate. Records of children treated for achalasia, over an 18-year period, were reviewed.Forty-eight children (median age at diagnosis 10 years; range 3-17 years) were identified. Twenty-eight patients were initially treated with Heller's myotomy (HM) and 20 with balloon dilatation (BD). At last follow-up (median 3 years; range 1-5.5 years), 43.8% (21/48) of children were symptom free. The number of asymptomatic children was significantly higher among those treated initially with HM compared to BD (HM 15/28, 53.6% BD 6/20, 30%, p < 0.05). All children who underwent BD required HM due to symptom recurrence. The median (range) total number of procedures was significantly higher in the BD group (BD 3 (1-7); HM 1 (1-5); p < 0.05) with a shorter time to the second intervention (BD 14 months, 95%CI 4-24; HM 58 months, 95%CI 38-79; p < 0.05). Of 108 procedures, esophageal perforation occurred in two children after HM (two out of 48 HM procedures in total, 4%) and one child after BD (1/60, 1.7%).

CONCLUSION

Less than half of children with achalasia are symptom free after initial treatment with either BD or HM. HM, however, when performed as first procedure, provided longer symptom-free period and reduced need for subsequent intervention. What is Known: • Balloon dilatation (BD) and Heller's myotomy (HM) are safe and effective treatment options for achalasia. • Controversy, however, exists regarding the most effective initial therapeutic approach. What is New: • HM with or without fundoplication may represent the initial therapeutic approach of choice. • Initial BD may negatively affect the outcome of a subsequent HM.

Для цитирования: Saliakellis Efstratios, Thapar Nikhil, Roebuck Derek, Cristofori Fernanda, Cross Kate, Kiely Edward, Curry Joseph, Lindley Keith, Borrelli Osvaldo. Long-term outcomes of Heller's myotomy and balloon dilatation in childhood achalasia.. European journal of pediatrics. 2017. DOI: 10.1007/s00431-017-2924-x.

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Обработка статьи · этапы, ошибки и управление
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