Rapid development of glioblastoma at the site of atypical meningioma resection.

The authors describe symptomatic presentation of glioblastoma within six months of resection of an atypical meningioma, at the same frontal parafalcine cerebral location. The patient had neither prior nor adjuvant radiotherapy nor known genetic risk factors. Possible links between invasive meningioma and transformation of adjacent glial cells or precursors to malignant glioma are discussed.