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Войти в исследования Zentralblatt fur Chirurgie · 2017
[Upper Jaw Malignoma: Results of a Monocentric Study Over 45 Years].
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Böhm Michaela, Kappler Matthias, Dauter Kevin, Reich Waldemar, Eckert Alexander Walter
Аннотация
BACKGROUND: Malignancies originating from the upper jaw are comparatively rare. This study aimed to evaluate the histological features, grading and staging in upper jaw carcinomas.
MATERIALS AND METHODS: A total of 199 malignancies of the maxillary sinus were analysed over 45 years and matched for age, gender, tumour size, and histological differentiation. Cases of squamous cell carcinomas were classified based on the TNM system, grading and five-year survival time.
RESULTS: Squamous cell carcinomas (60%) were the most frequent malignant tumours. The five-year survival rate of squamous cell carcinomas was more than 60% and hence superior to that of other oral squamous cell carcinomas, although approximately ⅔ of these tumours were T4 cases. More than 60% of squamous cell carcinomas were highly differentiated and characterised as G1 tumours. G2 and G3 tumours were considerably less common.
CONCLUSION: The risk of local recurrence was inversely disproportional to the grade of histological differentiation. All in all, an optimal surgical and radiological treatment may lead to good aesthetic and satisfactory functional results.
MATERIALS AND METHODS: A total of 199 malignancies of the maxillary sinus were analysed over 45 years and matched for age, gender, tumour size, and histological differentiation. Cases of squamous cell carcinomas were classified based on the TNM system, grading and five-year survival time.
RESULTS: Squamous cell carcinomas (60%) were the most frequent malignant tumours. The five-year survival rate of squamous cell carcinomas was more than 60% and hence superior to that of other oral squamous cell carcinomas, although approximately ⅔ of these tumours were T4 cases. More than 60% of squamous cell carcinomas were highly differentiated and characterised as G1 tumours. G2 and G3 tumours were considerably less common.
CONCLUSION: The risk of local recurrence was inversely disproportional to the grade of histological differentiation. All in all, an optimal surgical and radiological treatment may lead to good aesthetic and satisfactory functional results.