Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko · 2022
[Clinical and neuropsychological survey of patients with glioma of the corpus callosum].
СтатьяНазвание и аннотация: Оригинал на русском
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Buklina S B, Pitskhelauri D I, Beshplav Sh T
Аннотация
BACKGROUND: We found no reports devoted to a comprehensive analysis of cognitive impairment that can determine the quality of life in patients with glioma of the corpus callosum and topical affiliation of these disorders.
OBJECTIVE: Clinical and neuropsychological study of mental disorders in patients with gliomas of the corpus callosum, qualification of topical affiliation of the identified syndromes.
MATERIAL AND METHODS: We examined 30 patients with gliomas of the corpus callosum using the Luria's approach to clinical and neuropsychological survey.
RESULTS: We identified the features of cognitive impairment depending on localization of glioma in the corpus callosum. Non-spontaneity, reduced criticism to own condition up to denial of disease and memory impairment were more common in patients with anterior gliomas of the corpus callosum. These disorders can be associated with tumor spread into medial parts of frontal lobes. Subcortical symptoms including hypomimia, quiet dull voice, involuntary urination, severe disorders of dynamic praxis and memory impairment were more common in patients with glioma of the middle part of the corpus callosum. These disorders can be associated with dorsal tumor spread towards posterior part of the frontal lobe or ventrally towards the basal ganglia. Memory disorders more often manifested by Korsakoff syndrome prevailed in patients with posterior gliomas of the corpus callosum. This finding can be associated with ventral growth of tumor towards the fornix.
CONCLUSION: We identified the features of cognitive impairment depending on localization of glioma in the corpus callosum. Split-brain symptoms were rare in these patients and observed in lesions of middle and posterior parts of the corpus callosum only in 3 patients.
OBJECTIVE: Clinical and neuropsychological study of mental disorders in patients with gliomas of the corpus callosum, qualification of topical affiliation of the identified syndromes.
MATERIAL AND METHODS: We examined 30 patients with gliomas of the corpus callosum using the Luria's approach to clinical and neuropsychological survey.
RESULTS: We identified the features of cognitive impairment depending on localization of glioma in the corpus callosum. Non-spontaneity, reduced criticism to own condition up to denial of disease and memory impairment were more common in patients with anterior gliomas of the corpus callosum. These disorders can be associated with tumor spread into medial parts of frontal lobes. Subcortical symptoms including hypomimia, quiet dull voice, involuntary urination, severe disorders of dynamic praxis and memory impairment were more common in patients with glioma of the middle part of the corpus callosum. These disorders can be associated with dorsal tumor spread towards posterior part of the frontal lobe or ventrally towards the basal ganglia. Memory disorders more often manifested by Korsakoff syndrome prevailed in patients with posterior gliomas of the corpus callosum. This finding can be associated with ventral growth of tumor towards the fornix.
CONCLUSION: We identified the features of cognitive impairment depending on localization of glioma in the corpus callosum. Split-brain symptoms were rare in these patients and observed in lesions of middle and posterior parts of the corpus callosum only in 3 patients.