International journal of hematology · 1998
Second malignancy following treatment of acute lymphoblastic leukemia in children.
Клинический случайСтатьяНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Kubota M, Akiyama Y, Koishi S, Sawada M, Usami I, Lin Y W, Watanabe K, Takimoto T
Аннотация
Second malignancy is one of the serious late effects among long-term survivors of acute lymphoblastic leukemia (ALL) in children. Of 83 newly diagnosed pediatric ALL patients at our hospital between January 1980 and December 1995, four patients were found to have second malignancies. These included MDS/AML after B-ALL, rhabdomyosarcoma after early pre-B ALL, ependymoma after B-ALL, and astrocytoma after early pre-B ALL. The mean duration from initial ALL to second malignancy was 5.2 years. The possible causes of second malignancy in these patients are discussed in this report, along with a review of recent literature.
Предметные рубрики MeSH
Antineoplastic Combined Chemotherapy ProtocolsAstrocytomaBone Marrow TransplantationBrain NeoplasmsBurkitt LymphomaChildChild, PreschoolCohort StudiesCombined Modality TherapyCranial IrradiationDisease SusceptibilityEpendymomaFatal OutcomeFemaleHumansIncidenceLeukemia, MyeloidMaleMyelodysplastic SyndromesNeoplasms, Radiation-InducedNeoplasms, Second PrimaryParanasal Sinus NeoplasmsPrecursor B-Cell Lymphoblastic Leukemia-LymphomaPrecursor Cell Lymphoblastic Leukemia-LymphomaRhabdomyosarcomaSpinal Neoplasms