Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2009
[Clinical analysis of primary thymic lymphoma: a report of 27 cases].
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Wang Jian, Wang Wu-jun, Wu Hua, Wang Hao-fei, Zhang Zhen
Аннотация
OBJECTIVE: To investigate clinicopathologic features and optimal treatment of primary thymic lymphoma.
METHODS: Clinical records of 27 primary thymic lymphoma patients treated from 1990 to 2007 were reviewed.
RESULTS: Of the 27 patients, 8 received mastectomy and chemotherapy, 12 received excision of the thymic lesion and chemotherapy, 5 received chemotherapy alone, and 2 received lesion excision alone. 24 achieved complete remission after scheduled treatment, 1 achieved partial remission, and 2 patients had progressive disease. With a follow-up of 10 years and median 38 months, the 5-year overall and disease-free survival rates of the 27 patients were 47% and 23% respectively.
CONCLUSION: The main subtypes of primary thymic lymphoma are diffuse large B-cell lymphoma and peripheral T-cell lymphoma. The optimal sequence is radical operation followed by standard anthracycline-based regimens and radiotherapy.
METHODS: Clinical records of 27 primary thymic lymphoma patients treated from 1990 to 2007 were reviewed.
RESULTS: Of the 27 patients, 8 received mastectomy and chemotherapy, 12 received excision of the thymic lesion and chemotherapy, 5 received chemotherapy alone, and 2 received lesion excision alone. 24 achieved complete remission after scheduled treatment, 1 achieved partial remission, and 2 patients had progressive disease. With a follow-up of 10 years and median 38 months, the 5-year overall and disease-free survival rates of the 27 patients were 47% and 23% respectively.
CONCLUSION: The main subtypes of primary thymic lymphoma are diffuse large B-cell lymphoma and peripheral T-cell lymphoma. The optimal sequence is radical operation followed by standard anthracycline-based regimens and radiotherapy.