Cancer investigation · 2017
Primary Management of Squamous Cell Carcinoma of the Anal Canal: A 30-year Community Hospital Experience.
Клиническое исследованиеСтатьяНазвание и аннотация: Перевод пока не подготовлен
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Agarwal Mohit S, Jones Daniel A, Mendenhall Charles M, Morris Christopher G, Johns Andrew, McAfee William J, Mendenhall William M
Аннотация
We reviewed outcomes of 41 patients treated with curative-intent radiotherapy for anal canal carcinoma at a community hospital between 1985 and 2015. Twenty-six (63%) presented with stage I or II disease while 15 (37%) had stage III. Thirty-seven received definitive chemoradiation and 4 radiotherapy alone. Thirteen (31.7%) received ≤59.4Gy. Thirty-two (78%) were treated with 3-dimensional conformal radiotherapy while 9 (22%) received intensity-modulated radiotherapy. At 5 years, local control, regional control, freedom from distant metastasis, cause-specific survival, and overall survival were 80%, 98%, 88%, 77%, and 51%. Of those who received >59.4Gy, local control and overall survival were not improved.