Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference · 2019
Difference in Cortical Modulation of Walking between Persons with Multiple Sclerosis and Healthy Controls: An EEG pilot study.
СтатьяПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод пока не подготовлен
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Hoxha Armand, Glassen Michael, DeLuca John, Kwasnica Marek, Yue Guang, Saleh Soha
Аннотация
The overall goal of this study is to investigate the role of parietal cortex in the control of walking in persons with Multiple Sclerosis (pwMS). We examined within-brain connectivity and cortico-muscular connectivity as pwMS and healthy control (HC) participants walked on an instrumented treadmill. Cortical activity was collected using EEG, muscle activity was collected using wireless EMG modules, and gait data were obtained by using the instrumented treadmill. Results show significant activation of sensorimotor and posterior parietal cortex during walking in both groups. Connectivity between parietal (posterior cingulate cortex PCC) and premotor regions (pars opercularis), and between PCC and contralateral muscles were higher in the healthy control group. Higher connectivity correlated with higher walking speed.