Spine deformity · 2026
Complications and outcomes of spinal deformity correction in patient with open neural tube defects.
СтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Sergeenko Olga M, Savin Dmitry M, Arestova Yulia S, Dreval Maksim D, Kim Alexander V, Burtsev Alexander V, Ryabykh Sergey O
Аннотация
PURPOSE: To evaluate surgical complications, functional and neurological outcomes of spinal deformity correction in children who underwent open neural tube defects (ONTDs) repair earlier.
METHODS: We analyzed 65 patients with treated ONTDs (myelomeningocele and myeloschisis) who underwent spinal deformity correction at a single center from 2010 to 2023. Statistical methods included logistic regression to assess predictors of early and late complications.
RESULTS: Higher level of spinal cord malformation and spina bifida associated with higher rate of non-ambulatory status, C-shaped thoracolumbar scoliosis, lumbar kyphosis rate, and severity. Early complications occurred in 37% and included wound problems (31%), pneumothorax (6%), and screw malposition (5%). Late complications were noted in 39%, including late-onset implant exposure through skin (32%), rod fracture (14%), and screw loosening (10%). Intraoperative blood loss correlated with early wound complications (p = 0.004, OR 1.01, 95% CI 1.01-1.02) and pelvic fixation correlated with pseudoarthrosis (p = 0.027, OR 7.13, 95% CI 1.25-40.79). Neurological function remained stable during follow-up, whereas functional independence improved, but much less than in healthy individuals.
CONCLUSIONS: Level of spinal cord malformation in ONTDs correlated with walking status and deformity type and severity. Spinal deformity correction after ONTDs repair carries a high complication rate. Surgical intervention likely does not affect neurological and functional status significantly, but functional independence gradually improves.
METHODS: We analyzed 65 patients with treated ONTDs (myelomeningocele and myeloschisis) who underwent spinal deformity correction at a single center from 2010 to 2023. Statistical methods included logistic regression to assess predictors of early and late complications.
RESULTS: Higher level of spinal cord malformation and spina bifida associated with higher rate of non-ambulatory status, C-shaped thoracolumbar scoliosis, lumbar kyphosis rate, and severity. Early complications occurred in 37% and included wound problems (31%), pneumothorax (6%), and screw malposition (5%). Late complications were noted in 39%, including late-onset implant exposure through skin (32%), rod fracture (14%), and screw loosening (10%). Intraoperative blood loss correlated with early wound complications (p = 0.004, OR 1.01, 95% CI 1.01-1.02) and pelvic fixation correlated with pseudoarthrosis (p = 0.027, OR 7.13, 95% CI 1.25-40.79). Neurological function remained stable during follow-up, whereas functional independence improved, but much less than in healthy individuals.
CONCLUSIONS: Level of spinal cord malformation in ONTDs correlated with walking status and deformity type and severity. Spinal deformity correction after ONTDs repair carries a high complication rate. Surgical intervention likely does not affect neurological and functional status significantly, but functional independence gradually improves.