Primary retroperitoneal angiosarcoma with eosinophilic globules. A combined light-microscopic, immunohistochemical, and ultrastructural study.

A poorly differentiated primary retroperitoneal angiosarcoma with abundant intracytoplasmic and extracytoplasmic eosinophilic globules containing alpha 1-antitrypsin and alpha 1-antichymotrypsin is presented. Recognition of these globules may facilitate future diagnoses of the neoplasm in this or other locations. To the best of our knowledge, this is the first article on a primary angiosarcoma of the retroperitoneum.