Pediatric hematology and oncology · 1991
Rhabdomyosarcoma with primary osteolytic lesions simulating non-Hodgkin's lymphoma.
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Locatelli F, Tonani P, Porta F, Zecca M, Beluffi G, Fiori P, Rosso R, Paulli M, Basso G, Invernizzi R
Аннотация
We report the case of an 8-year-old child presenting with the pathological fracture of two vertebral bodies due to bone lytic lesions. Physical and instrumental examinations did not show any further evidence of disease. However, bone marrow aspirate showed an infiltrate of poorly differentiated cells. When the child was transferred to the Department of Pediatrics, lymphoblastic leukemia was suspected. Although the morphology of the bone marrow biopsy could have suggested a lymphoblastic lymphoma, further immunochemical and immunological studies together with the study of tissue surface antigens resulted in a diagnosis of embryonal rhabdomyosarcoma with an unusual presentation.
Предметные рубрики MeSH
Antigens, DifferentiationBiomarkers, TumorBone Marrow ExaminationChildDiagnosis, DifferentialDiagnostic ErrorsFractures, SpontaneousHumansHypercalcemiaLumbar VertebraeLung NeoplasmsLymphoma, Non-HodgkinMaleNeoplasms, Unknown PrimaryOsteolysisOsteoporosisPrecursor Cell Lymphoblastic Leukemia-LymphomaRhabdomyosarcomaSoft Tissue NeoplasmsSpinal Fractures