Mechanosensitive Enteric Neurons (MEN) at Work.

In the last decade, we characterized an enteric neuronal subpopulation of multifunctional mechanosensitive enteric neurons (MEN) while studying the gastrointestinal peristalsis. MEN have been described in a variety of gastrointestinal regions and species. This chapter summarizes existing data on MEN, describing their proportions, firing behaviors, adaptation musters, and chemical phenotypes. We also discuss MEN sensitivity to different mechanical stimulus qualities such as compression and tension along with pharmacology of their responses.