European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology · 2003
Pattern of recurrence after surgery in adenocarcinoma of the gastro-oesophageal junction.
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de Manzoni G, Pedrazzani C, Pasini F, Durante E, Gabbani M, Grandinetti A, Guglielmi A, Griso C, Cordiano C
Аннотация
AIMS: This study reports mode, timing and predictive factors of recurrence after curative surgery for cardia cancer.
METHODS: A prospective study in a series of 92 curatively (R0) resected patients from 1988 to 2002.
RESULTS: The 5-year recurrence rate was 71%. Lymph node involvement was the only predictor of recurrence. No patients with more than 6 metastatic nodes were free from relapse 2 years after surgery. Locoregional, peritoneal and haematogenous relapses showed a similar median recurrence time (12, 10 and 12 months, respectively), 80% occurred within 24 months.
CONCLUSIONS: Few patients can be cured by surgery, lymph nodal involvement is the only predictor of recurrence.
METHODS: A prospective study in a series of 92 curatively (R0) resected patients from 1988 to 2002.
RESULTS: The 5-year recurrence rate was 71%. Lymph node involvement was the only predictor of recurrence. No patients with more than 6 metastatic nodes were free from relapse 2 years after surgery. Locoregional, peritoneal and haematogenous relapses showed a similar median recurrence time (12, 10 and 12 months, respectively), 80% occurred within 24 months.
CONCLUSIONS: Few patients can be cured by surgery, lymph nodal involvement is the only predictor of recurrence.