EEG Measurement for Suppression in Refractive Amblyopia and Push-Pull Perception Efficacy.

In order to evaluate refractive amblyopia suppression and understand the neural mechanism of amblyopia suppression and push-pull perception training, we recorded the EEG of refractive amblyopia children before, during, and after push-pull perception training. We compared the brain activity in different states through the steady-state visual evoked potentials (SSVEPs) response and power topography and compared them with normal children. We found that amblyopic and fellow eyes have different performances in fundamental and harmonic frequency responses. They also show different characteristics when be masked. Push-pull perception training improved the SSVEP performance of amblyopia children by reducing the SSVEP response difference between eyes and improving the intermodulation frequency response. The result of topography showed that push-pull perception reduced the alpha power of occipital and temporal lobes, which was conducive to improving binocular function. The changes of intermodulation response and occipital alpha power were significantly correlated with the clinical indicator. Thus, EEG is a potential method to measure amblyopia suppression and the efficacy of push-pull perception.