Oral and maxillofacial surgery · 2011
Management of malignant parotid tumors.
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Papadogeorgakis Nikolaos, Goutzanis Lampros, Petsinis Vassilis, Alexandridis Constantinos
Аннотация
INTRODUCTION: The aims of this study were to review our experience in the treatment of malignant parotid tumors in material from one center over a 12-year period and to assess treatment outcome and particularly survival.
MATERIALS AND METHODS: Thirty-one patients treated primarily by surgery were included in the study. Complete data regarding the demographic details of the patients, tumor stage, presence of regional/distant metastases, treatment, tumor histology, grade, and follow up were compiled. With reference to the extent of tissue removed, partial superficial parotidectomy was performed in 11 patients, superficial parotidectomy, in 14 patients, and total radical parotidectomy, in six patients.
RESULTS: The median time of follow-up was 64 months, ranging from 8 to 144 months. Eight patients developed recurrences. Six patients died within the follow-up time. The overall survival rates at 5 and 10 years were 82.2% and 76.7%, respectively. The 5- and 10-year disease-free survival rates were 74.8% and 69.8%, respectively.
DISCUSSION: For patients with malignant parotid tumors, the treatment should be individualized according to the findings of each specific case, and regarding surgery, particular care and attention should be paid to maintaining all or part of the facial nerve whenever possible.
MATERIALS AND METHODS: Thirty-one patients treated primarily by surgery were included in the study. Complete data regarding the demographic details of the patients, tumor stage, presence of regional/distant metastases, treatment, tumor histology, grade, and follow up were compiled. With reference to the extent of tissue removed, partial superficial parotidectomy was performed in 11 patients, superficial parotidectomy, in 14 patients, and total radical parotidectomy, in six patients.
RESULTS: The median time of follow-up was 64 months, ranging from 8 to 144 months. Eight patients developed recurrences. Six patients died within the follow-up time. The overall survival rates at 5 and 10 years were 82.2% and 76.7%, respectively. The 5- and 10-year disease-free survival rates were 74.8% and 69.8%, respectively.
DISCUSSION: For patients with malignant parotid tumors, the treatment should be individualized according to the findings of each specific case, and regarding surgery, particular care and attention should be paid to maintaining all or part of the facial nerve whenever possible.
Предметные рубрики MeSH
AgedAged, 80 and overBiopsy, NeedleChemoradiotherapy, AdjuvantCombined Modality TherapyDiagnostic ImagingDisease-Free SurvivalFemaleFollow-Up StudiesHumansKaplan-Meier EstimateLymphatic MetastasisMaleMetastasectomyMiddle AgedNeck DissectionNeoplasm StagingParotid GlandParotid NeoplasmsTreatment Outcome