The Laryngoscope · 2015
Complex nontuberculous mycobacterial cervicofacial lymphadenitis: What is the optimal approach?
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Gonzalez Cristian D, Petersen Matthew G, Miller Matthew, Park Albert H, Wilson Kevin F
Аннотация
OBJECTIVES/HYPOTHESIS: Assess the role of combined antimicrobial and surgical therapy for difficult-to-treat nontuberculous mycobacteria (NTM) lesions of the head and neck in children.
STUDY DESIGN: Retrospective cohort.
METHODS: Retrospective review of pediatric head and neck NTM lesions at a tertiary children's hospital from 1999 to 2012.
RESULTS: Seventy-one children were diagnosed with NTM lesions. Age of presentation ranged between 7 and 204 months of age. Most patients (62%) had multiple lesions. Treatments included incision and drainage, curettage, antibiotics, excision, and any combination of surgery and antibiotics. Upon initial presentation, the most common treatment was surgical excision alone (n = 34) with a high complication rate (50%). In 18 cases, patients were initially treated with a combination of antibiotics and surgical excision due to the extent or location of the lesion(s). Complication rate in these patients was also high (67%). The most common complications in surgically excised NTM lesions included temporary or persistent facial nerve dysfunction (24.6%), poor wound healing/scarring (10.8%), and Frey's syndrome (6.2%).
CONCLUSIONS: Surgical excision with or without medical therapy for NTM cervicofacial lymphadenitis in high-risk regions commonly resulted in marginal mandibular nerve dysfunction (24.6%). Postoperative facial nerve weakness generally resolved within a year. High rates of complications and a lack of proven best approaches suggest tailoring the approach to address the potential risks in that particular patient based on location and severity.
LEVEL OF EVIDENCE: 4 Laryngoscope, 126:1677-1680, 2016.
STUDY DESIGN: Retrospective cohort.
METHODS: Retrospective review of pediatric head and neck NTM lesions at a tertiary children's hospital from 1999 to 2012.
RESULTS: Seventy-one children were diagnosed with NTM lesions. Age of presentation ranged between 7 and 204 months of age. Most patients (62%) had multiple lesions. Treatments included incision and drainage, curettage, antibiotics, excision, and any combination of surgery and antibiotics. Upon initial presentation, the most common treatment was surgical excision alone (n = 34) with a high complication rate (50%). In 18 cases, patients were initially treated with a combination of antibiotics and surgical excision due to the extent or location of the lesion(s). Complication rate in these patients was also high (67%). The most common complications in surgically excised NTM lesions included temporary or persistent facial nerve dysfunction (24.6%), poor wound healing/scarring (10.8%), and Frey's syndrome (6.2%).
CONCLUSIONS: Surgical excision with or without medical therapy for NTM cervicofacial lymphadenitis in high-risk regions commonly resulted in marginal mandibular nerve dysfunction (24.6%). Postoperative facial nerve weakness generally resolved within a year. High rates of complications and a lack of proven best approaches suggest tailoring the approach to address the potential risks in that particular patient based on location and severity.
LEVEL OF EVIDENCE: 4 Laryngoscope, 126:1677-1680, 2016.