Medical science monitor : international medical journal of experimental and clinical research · 2014
Pediatric head and neck tumors: an intra-demographic analysis using the SEER* database.
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Cesmebasi Alper, Gabriel Abigail, Niku Daniel, Bukala Karolina, Donnelly Joseph, Fields Paul J, Tubbs R Shane, Loukas Marios
Аннотация
BACKGROUND: The aim of this study was to determine the most frequently presenting tumors exclusive to the head and neck within the pediatric population, and to identify racial disparities within the existing incidence rates.
MATERIAL/METHODS: The population-based Surveillance, Epidemiology, and End Results (SEER) registry was utilized to identify the frequency and incidence rates of various tumors found exclusively in the head and neck, diagnosed between 1973 and 2008 in pediatric patients. The tumor categories were based on those defined by the US Department of Health and Human Services National Cancer Institute (NCI). Proportional comparisons were applied to evaluate the intra-demographic incidence rate differences.
RESULTS: Among the 11 categories defined, the 5 most prevalent head and neck cancers within the pediatric population were salivary gland tumors (n=319); followed by nasopharyngeal neoplasms (n=311); tumors of the nose, nasal cavity and middle ear (n=208); gum and other mouth tumors (n=134); and glossal tumors (n=61). Proportional comparisons between racial frequency rates indicated that salivary gland tumors were greatest among white pediatric patients (n=246, CI=0.8 to 14.1%, p<.05). Nasopharyngeal cancers were highest among blacks (CI=-26.8 to -12.1%) and other races (CI=-23.6 to -3.4%) relative to the white population.
CONCLUSIONS: Salivary gland tumors were the most commonly seen head and neck tumors overall among pediatric patients between 1973 and 2008. Incidence rate differences between white, black, and other racial background pediatric patients revealed that overall, head and neck tumors are most prevalent among pediatric patients within the white ethnic population, while nasopharyngeal tumors showed a strong prevalence in blacks and other ethnic populations.
MATERIAL/METHODS: The population-based Surveillance, Epidemiology, and End Results (SEER) registry was utilized to identify the frequency and incidence rates of various tumors found exclusively in the head and neck, diagnosed between 1973 and 2008 in pediatric patients. The tumor categories were based on those defined by the US Department of Health and Human Services National Cancer Institute (NCI). Proportional comparisons were applied to evaluate the intra-demographic incidence rate differences.
RESULTS: Among the 11 categories defined, the 5 most prevalent head and neck cancers within the pediatric population were salivary gland tumors (n=319); followed by nasopharyngeal neoplasms (n=311); tumors of the nose, nasal cavity and middle ear (n=208); gum and other mouth tumors (n=134); and glossal tumors (n=61). Proportional comparisons between racial frequency rates indicated that salivary gland tumors were greatest among white pediatric patients (n=246, CI=0.8 to 14.1%, p<.05). Nasopharyngeal cancers were highest among blacks (CI=-26.8 to -12.1%) and other races (CI=-23.6 to -3.4%) relative to the white population.
CONCLUSIONS: Salivary gland tumors were the most commonly seen head and neck tumors overall among pediatric patients between 1973 and 2008. Incidence rate differences between white, black, and other racial background pediatric patients revealed that overall, head and neck tumors are most prevalent among pediatric patients within the white ethnic population, while nasopharyngeal tumors showed a strong prevalence in blacks and other ethnic populations.